Machine Learning Research Engineer

Company: One Nucleus Limited
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Location: Cambridge
Job Description:

Overview

Constructive Bio is a VC-backed biotechnology startup based in Whittlesford, Cambridge. Our unique technology turns living cells into biofactories, creating sustainable new materials and therapeutics. With full control of the genetic sequence and code, we are exploring chemical space previously unreached by natural biology.

Responsibilities

  • Turn prototypes into production systems; work fluidly across the biology-ML boundary.
  • Build and maintain our codebase, scale training pipelines, and fine-tune state-of-the-art sequence models on in-house data.
  • Collaborate closely with experimental biologists; support generative models that inform wet-lab design cycles.

About the role

As our second ML hire, you’ll work directly with our ML Scientist to define engineering standards and infrastructure that will shape everything that follows. The role carries real ownership — and real exposure to the full stack of modern biological ML.

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Posted: April 5th, 2026