Senior Scientist – Cancer Immunology

We are partnered with an immuno-oncology focused biotech in Oxford seeking to hire a Senior Scientist with expertise in Cancer Immunology. This role requires a PhD in a relevant field. Prior industry experience is highly desirable and familiarity with bioinformatics is a plus.

Responsibilities:

• Contribute to a collaborative, high-standard research environment with strong focus on reproducibility, data integrity, and regulatory compliance
• Support translational research strategy and help shape scientific direction within a small, multidisciplinary discovery team
• Design and optimise experimental models, including 2D and organoid systems
• Develop and refine macrophage culture, maturation, and functional activation assays
• Establish co-culture systems and cell-based assays to assess immune cell activity and cytokine responses
• Troubleshoot experimental challenges and ensure robust, high-quality data generation for drug discovery programmes
• Analyse, interpret, and communicate experimental findings to guide project progression

Requirements:

• Extensive experience handling and isolating human immune cells from primary samples
• Strong experience in immune cell culture, expansion, and functional immunology assays
• Expertise in macrophage biology, including differentiation and maturation studies
• Hands-on experience with flow cytometry, immune phenotyping, and cytotoxicity assays
• Ability to design and execute robust cellular immunology assays

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