About Us
Portal Biotech has built the world’s only platform capable of sequencing full-length proteins at the single-molecule level. Using our nanopore technology, we read intact proteins of any size, capturing both sequence and post-translational modifications in a way no other system can. This opens up entirely new ways to understand protein biology, with applications across drug discovery, diagnostics, and biosecurity.Our technology works and customers are engaging. We’re now focused on scaling, turning breakthrough science into products that deliver real biological insight as we move beyond Series A towards global product launch
About the role
We are seeking a Senior Process Engineer to define, develop, and optimise manufacturing processes within our pilot manufacturing operation. Based at our London site, this is a primarily on‑site, hands‑on role.
You will be responsible for ensuring manufacturing processes are robust, repeatable, and capable of supporting future scale. This role will focus on process performance, validation, and continuous improvement.
In the early phase, this role will include active participation in manufacturing activities on the production line, ensuring processes are developed and refined based on real operational conditions.
Tasks and responsibilities
- Define and develop manufacturing processes across all production stages
- Improve process robustness, repeatability, and performance
- Define and maintain critical process parameters (CPPs)
- Lead engineering verification and validation execution
- Drive yield improvement and reduction of process variability
- Lead technical troubleshooting and root cause analysis
- Support development of continuous manufacturing flow
- Work closely with Operational Excellence on process control and improvement
- Support transfer of processes into stable, repeatable operations
- Participate in manufacturing activities during early pilot phases
Qualifications
- Degree in Engineering, Biochemistry, Manufacturing, or related discipline, or equivalent experience
- Strong experience in process development or manufacturing engineering
- Experience with validation and process optimisation
- Strong analytical and problem‑solving skills
- Experience working in structured or regulated environments
- Ability to work cross‑functionally
Desirable
- Experience in pilot or early‑stage manufacturing environments
- Experience in regulated industries (e.g. medical devices, biotech, pharmaceuticals)
- Familiarity with statistical methods or process control
- Experience with automated or semi‑automated systems
This is a hands‑on role within an early‑stage manufacturing team, where you will help build and refine processes based on real operational experience. You will play a key part in establishing robust, scalable systems that will underpin future manufacturing capability.
We offer a competitive salary and benefits package. If you are passionate about building robust manufacturing systems and contributing to the delivery of innovative scientific technologies, we encourage you to apply!
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