District Manager - Boston, MA

Company: Ionis Pharmaceuticals, Inc.

Location: Boston

Posted: April 11th, 2026

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Ionis Pharmaceuticals, Inc. provided pay range

This range is provided by Ionis Pharmaceuticals, Inc.. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$149,133.00/yr - $195,000.00/yr

DESCRIPTION:

Ionis Pharmaceuticals, Inc., is headquartered in Carlsbad, California, with offices in Boston, Massachusetts, and Dublin, Ireland. For more than 30 years, Ionis has been the leader in RNA-targeted therapy, pioneering new markets and changing standards of care with our novel antisense technology. Ionis currently has three marketed medicines and a premier late-stage pipeline highlighted by industry-leading cardiovascular and neurological franchises. Our scientific innovation began and continues with the knowledge that sick people depend on us, which fuels our vision to become the undisputed leader in genetic medicine, utilizing a multi-platform approach to discover, develop and deliver life-transforming therapies.

As the first company to fully harness the power of RNA technology for human therapeutics, Ionis’ platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. We are building upon our innovative research and drug development excellence to provide greater value to patients, and we are well positioned financially to deliver on our strategic goals.

Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together a diverse group of individuals with different skill sets and perspectives into this creative environment to be part of a productive and inclusive team. While acknowledging people are actively engaged in hybrid/remote work, we continue to invest time, money, and energy into making our workplace locations a place where our culture and employees can thrive. We believe engaging on a day-to-day basis, in person, builds solid and lasting relationships, and contributes positively to our culture and innovation. From the heart of our stunning Carlsbad campus, we aim to provide a central connection point for all our employees. These facilities give us the opportunity to connect cross-functionally, collaborate and to build on the success of our business as we continue to grow. Join us and experience our unique culture while you develop and expand your career.

POSITION:

The District Manager is a field-based role responsible for building and leading a high performing sales team of Clinical Specialists to build upon the launch of Ionis’s first wholly owned commercial product, specifically for an ultra-rare disease called Familial Chylomicronemia Syndrome (FCS) and any future follow-on indications. This role reports to the Regional Executive Director. The District Manager will be responsible for achieving/exceeding sales goals by executing the strategic vision set for the region aligned to brand strategy and effectively coaching, motivating, training, hiring and retaining talent with a high level of accountability for delivering results. This successful candidate will partner with their cross-functional teammates to understand and address the unique needs of their customers, ensuring the customer and patient experience is held to the highest standards in a compliant manner.

RESPONSIBILITIES:

The District Manager will possess a deep understanding of the healthcare market in their respective districts and the FCS and severe hypertriglyceridemia (sHTG) community, including the key customers and accounts treating cardiovascular and lipid related diseases. This will include understanding of the needs of each customer in their pursuit of improved patient outcomes by advocating for patients suffering from FCS. The District Manager will achieve this by building, maintaining and leveraging networks and relationships in the local healthcare system and leading the Sales Specialists to develop and execute effective plans to meet customer and Ionis goals. The District Manager will serve as a leader: build, lead, coach, train, motivate, and inspire a diverse team of people with deep functional and therapeutic area expertise engaging effectively and compliantly across the therapeutic field teams to bring a novel treatment to FCS patients.

Strategy and Innovation

Performance Management

Cross-Functional Collaboration

QUALIFICATIONS

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

The pay scale for this position is $149,133 to $195,000

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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