Medical Director - Neurodegenerative Diseases (Alzheimer's Disease)
Contract | Outside IR35
Hybrid - 2 days per week onsite (Welwyn Garden City area)
The Opportunity
An innovative global biopharmaceutical organisation is seeking an experienced Medical Director - Neurodegenerative Diseases to support late-stage clinical development programmes in CNS, with a primary focus on Alzheimer's disease.
This role offers the opportunity to contribute to pivotal Phase III programmes aimed at addressing significant unmet medical needs in neurodegeneration. You will play a central role in translating cutting‑edge science into high‑impact clinical strategies, helping to bring potentially transformative therapies to patients.
This is a high‑visibility, cross‑functional leadership position within a global matrix environment.
Key Responsibilities
- Support the design and execution of global clinical development strategies across all phases, with strong emphasis on Phase III programmes
- Provide medical monitoring for ongoing interventional clinical trials
- Contribute to protocol development, study design, and data interpretation
- Partner closely with cross‑functional teams including Clinical Operations, Safety, Biostatistics, Regulatory Affairs, Clinical Pharmacology, Biomarkers, and Research
- Support preparation for regulatory interactions and health authority engagements
- Participate in advisory boards and engage with external investigators and key opinion leaders
- Translate clinical data into strategic development decisions
Candidate Profile
Essential
- MD or MD/PhD (medical degree required)
- Minimum 5 years' experience in longitudinal clinical research, including hands‑on clinical trial experience (industry or academic setting)
- Strong experience supporting or leading Phase II‑III development programmes, with particular focus on Phase III
- Experience in medical monitoring of interventional studies
- Proven ability to work effectively within global, cross‑functional matrix teams
- Experience interfacing with regulatory authorities and external stakeholders
- Excellent written and verbal scientific communication skills
Desirable
- Direct experience in neurodegenerative diseases, particularly Alzheimer's disease
- Experience designing late‑stage CNS development strategies
- Prior experience within a global pharmaceutical or biotechnology organisation
- Involvement in regulatory submissions
- Peer‑reviewed publications in neurology or neurodegeneration
Who This Role Would Suit
- Brings strong late‑stage CNS clinical development expertise
- Is confident in medical monitoring and protocol design
- Operates effectively in a complex, global matrix structure
- Is comfortable engaging with regulators and external experts
- Combines scientific rigour with strategic thinking
Work Arrangement & Contract Details
- Contract position
- Outside IR35
- Hybrid working: 2 days per week onsite in the Welwyn Garden City area
If you are passionate about advancing innovation in neurodegenerative disease and want to contribute to high‑impact late‑stage programmes, we encourage you to apply.
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