Cytokinetics is a late-stage, specialty cardiovascular biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which cardiac muscle performance is compromised. As a leader in muscle biology and the mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to impact myocardial muscle function and contractility.
As a subject matter expert in Medical Affairs, the Senior Director Medical Affairs UK will oversee all medical initiatives throughout the UK and contribute to the development and implementation of global medical affairs strategies. They will provide support to internal colleagues and collaborate closely with the Global & European Medical Affairs teams to ensure high strategic and scientific standards by resolving medical issues and providing critical input in the development of medical documents (publications, external scientific communications, standard response letters, product materials, research ideas, internal training materials, etc.). The Medical Director, under the guidance of the VP of Medical Affairs Europe to whom s/he will be reporting (and dotted line to the UK leader), will ensure strategic partnerships with key external opinion leaders and academic institutions in the UK market, and represent Medical Affairs externally through presentations at advisory boards, key scientific meetings, and interactions with our key investigators. In addition, the Medical Director will work cross-functionally with other colleagues to provide expertise on varied workstreams, including pre-launch and launch activities related to late-stage assets.
The role is hybrid twice per week in London office.
Responsibilities
- Serves as an integral component of the Medical Affairs contribution to the UK launch of our late-stage cardiovascular clinical compounds, including:
- Implementation of the Country Plan of Action based on the Global and European Medical Affairs Plan,
- Execution of medical pre-launch and launch activities,
- Education of Cardiovascular HCPs (heart failure and hypertrophic cardiomyopathy) regarding the clinical profile of our CV compounds and their place in therapy
- Can speak to the mechanism of action of the compounds and their development, including Phase I-IV studies, at a detailed scientific level in a reactive conversation with key opinion leaders.
- Provide day‐to‐day medical guidance while working closely on joint projects with other members of the Medical Affairs team, the Countries leadership, other departments internally and our business partners.
- Projects may include scientific congress/conference strategy and planning, advisory boards, field force training, review of medical information standard response letters, health economics and epidemiology analyses, and marketing/policy related projects.
- Represent the company at Medical Congresses and ensure Medical Affairs coverage, including scientific session attendance and reporting, and information booth support.
- Represent the company in patient groups and associations.
- Provide scientific input into publication strategy and review abstracts and posters for presentation at scientific meetings and manuscripts for publication.
- Participate in appropriate cross‐functional and cross‐company Medical and Commercial teams in the UK to inform brand strategies and tactics and represent Medical Affairs.
- Liaise with Global & European Medical Affairs and R&D colleagues to develop and maintain timely and relevant product expertise for the region.
- Provide input into medical education, grant, and sponsorship review.
- Provide clinical and scientific support in responding to inquiries from healthcare professionals.
- Participate as medical reviewer in the Medical Review Committee and the Promotional Materials Review Committee
- Data Generation and Presentation
- Present data at company advisory board meetings and training programs
- Collaborate with R&D and HEOR in data generation projects to address identified medical data gaps for the UK
- Help identify and effectively interact with opinion leaders to engage in scientific exchange to meet the needs of patients and the medical community.
- Collaborate with Market Access and the HEOR function to define research strategy and design of studies, including the generation of real-world evidence and cost-effectiveness analyses.
- Provide support for and collaborate with the field medical teams in the UK and support reactive material development to address healthcare professional inquiries.
- Upon initiation of a Phase 4 program, participate in the review and adjudication of investigator-sponsored study research proposals.
Qualifications
- MD/MBBS with strong Medical Affairs experience. Cardiovascular experience preferred, clinical experience desirable. Position will be filled at a Director level (i.e. Director, or Senior Director) commensurate with experience. 7 years of pharmaceutical industry experience preferred.
- Medical Affairs experience in the UK (with particular knowledge of the Countries market) with medicine approvals and peri-launch and launch activities.
- Background in academic medicine, clinical research, and familiarity with study design, biostatistics and epidemiology desirable.
- Proven ability to work independently and as a member of an integrated, interdisciplinary team in carrying out assigned responsibilities.
- Must be analytical and articulate in both oral and writing skills, possess excellent presentation skills, with a demonstrated ability to communicate well with others at varying professional levels.
- Familiarity with relevant regulatory authorization requirements and other key local authorities in the regional pharmaceutical industry.
- Ability to think broadly about scientific communications and the impact on medical content.
- Business fluent in English. Knowledge of other European languages are a plus.
- Proficiency with Microsoft Office
- Ability to travel within the UK, across Europe, and internationally (~35% of time)
Cytokinetics is an Equal Opportunity Employer
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