Clinical Trial Practitioner/Research Nurse

Vacancy at University College London Hospitals NHS Foundation Trust

The Research Nurse/Clinical Trials Practitioner is an autonomous specialist working within the multi‑disciplinary team. The post holder will take responsibility for the co‑ordination and management of a clinical research portfolio comprising in‑house, national and international phase II and III clinical trials in hematological malignancies. The post is clinically based to support research in all oncology and haematological malignancies, and post holders will be expected to provide cross‑cover for members of the team.

Responsibilities will include education of patients and colleagues, coordination of care of patients on trials, collection and preparation of biological samples, collection of trial data, and monitoring of the expected and unexpected side effects of drugs and other treatment modalities. The post holder will be expected to develop specialised skills and knowledge relating to the conduct of clinical trials, the therapies and the relevant disease sites. The post holder will be expected to have sufficient skills to enable patients to make informed choices concerning their involvement in clinical trials by providing advice and information and acting as the patient’s advocate.

Key Responsibilities

• Coordinate and conduct in‑house, commercial and non‑commercial national and international Phase I, II and III clinical trials.
• Be accountable for the documentation of trial data according to ICH GCP guidelines.
• Apply critical appraisal skills in evaluating research protocols.
• Demonstrate autonomy and ability to collaborate within a multidisciplinary healthcare team, identifying and meeting the needs of patients and their families during various stages of the healthcare continuum.
• Coordinate and monitor the care of patients on clinical trials.
• Educate the multidisciplinary team about the portfolio of clinical trials.
• Act as a primary point of contact for patients in specific trials.
• Educate patients and families about clinical trials, including the objectives, scientific rationale, treatment schedule, side effects and follow‑up plan.
• Develop programs of care for patients taking part in clinical trials.
• Mentor data managers and clinical trial practitioners.
• Provide cross‑cover for other research nurses, trial practitioners, data managers and assistants working in the clinical trials unit as directed by the Clinical Trials Manager.
• Take personal responsibility for promoting a safe environment and safe patient care by identifying areas of risk and following the incident, serious incidents and near‑misses reporting policy and procedure.

Hospital Sites

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National Throat, Nose and Ear Hospital
• Eastman Dental Hospital
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre
• The Hospital for Tropical Diseases
• University College Hospitals at Westmoreland Street

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top‑quality patient care, excellent education, and world‑class research.

We provide first‑class acute and specialist services across eight sites and are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world‑class support services including critical care, imaging, nuclear medicine and pathology. At UCLH, we have a real ‘One Team’ ethos, and our values – safety, kindness, teamwork and improvement – are central to the way we work. This is supported by our staff, who voted us as the #1 NHS Acute Trust to work for in the whole of England.

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

UCLH recognises the benefits of flexible working for staff—To find out more, visit: Flexible working. To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

This advert closes on Wednesday 21 Jan 2026.

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