Principal Research Scientist II – Cell Depletion Team Lead

Principal Research Scientist II – Cell Depletion Team Lead

• Full-time
• Workday Global Grade: 19
• Role Focus: Novel Therapeutics Discovery – Cell Depletion Team Lead
• Location: Oxford, UK

At DJS‑AbbVie, we are committed to advancing new therapeutics and translating novel immunological science into innovative R&D programmes. We seek an accomplished drug hunter to lead a team of 5+ scientists, delivering key translational pharmacodynamic data packages and drug candidates to lead programmes from conception to IND.

Key Responsibilities

• Develop and deliver drug discovery strategy in alignment with immunology strategy and key scientific objectives.
• Lead a team of 5+ direct reports, ranging from entry level to Principal Scientist level.
• Build scientific capability within the team and foster a strong drug discovery mindset.
• Develop strong working relationships with key partner functions, including target identification and evaluation and disease discovery teams.
• Act as biology or molecule lead on pipeline programmes, providing cross‑functional leadership as teams form around assets.
• Collaborate with colleagues across immunology discovery research, clinical development, development sciences and precision medicine.
• Serve as a recognised scientific expert within the organisation in your specialist mechanism of action.
• Proactively share knowledge, mentor colleagues and support the development of functional capability.
• Ensure high‑quality project planning through sound experimental design, early risk assessment and robust contingency planning.
• Identify and evaluate emerging scientific trends and translate relevant insights into functional objectives.
• Apply imagination and innovation to create and implement new or improved approaches and breakthrough ideas.
• Present scientific concepts and results to scientific and non‑scientific audiences, including senior stakeholders and external partners.
• Experience across multiple drug discovery programmes, including at least one programme taken from early discovery to GLP tox start with a depletion modality.

Qualifications

• Bachelor’s degree in a science‑related field with typically 16+ years of relevant experience.
• Master’s degree or PharmD with typically 14+ years of relevant experience.
• Proven ability to innovate and deliver new or improved lead and candidate molecules.
• Strong relationship‑building skills and the ability to work effectively with diverse internal and external collaborators.
• Recognised as an expert in your discipline, internally and ideally externally.
• Excellent scientific communication and presentation skills, with the ability to influence across functions and levels.
• BS/MS or PhD or equivalent experience in a relevant scientific area.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer / Veterans / Disabled.

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

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