Study Doctor (Human Challenge Facility)
Location: Liverpool
Salary: £52,656 – £65,048
Contract: Fixed term until 19/08/27
Flexible working arrangements between 0.4 and 1.0 FTE available
Role includes evening, weekend, and on-call commitments with additional payments in line with rota requirements.
Overview
Liverpool School of Tropical Medicine (LSTM) is a globally recognised centre of excellence for teaching and research in tropical diseases. Recently ranked in the top 5.3% of universities in the world, we are proud of the work we do and the impact this has on the people who need our help most.
We are seeking a motivated and proactive Study Doctor to join our Human Challenge Facility within Clinical Sciences. This is an exciting opportunity to contribute to innovative experimental medicine and controlled human infection studies that aim to accelerate the development of vaccines, diagnostics and therapeutics for populations most affected by infectious diseases globally.
Working within a multidisciplinary clinical research environment, you will provide high-quality medical oversight for research participants while ensuring studies are delivered safely, ethically and in compliance with Good Clinical Practice (GCP) and regulatory requirements.
This role is suitable for doctors with an interest in infectious diseases, immunology, acute medicine, public health, clinical pharmacology or clinical research.
Key Responsibilities
Clinical Duties
- Support human challenge and clinical trial portfolio, putting the health, safety and well-being of participants at the forefront of all activities
- Provide medical oversight of trial participants
- Maintain an excellent standard of participant care in accordance with ICH GCP, UK Policy Framework for Health and Social Care Research, LSTM Standard Operating Procedures and General Medical Council (GMC) requirements.
- Screening participants for eligibility to enter clinical studies, including providing information to participants about the study and taking informed consent
- Physical health checks including physical examination
- Interpreting ECGs, venepuncture, reviewing laboratory results for clinical significance
- Clinical review of participants before trial procedures to ensure it is safe to proceed
- Collecting information from participants relating to adverse events, reporting and assessing these events according to relevant protocols and regulations
- Provide management of medical emergencies
- Escalating clinical issues to the appropriate Investigator
- Ensure safe prescription of trial medications as per protocol and relevant regulations
- Maintain clinical skills in line with local and NHS policy
Research Responsibilities
- Work to Good Clinical Practice standards at all times
- Data collection and entry into eCRFs, respond to data management queries in a timely fashion
- Complete all relevant study training including HCF SOPs within the mandated timelines
- Contribute to study design through protocol reviews and drafting, contribute to participant facing documents
- Support study set up activities including reviewing and advising on regulatory applications (HRA, REC, MHRA) as required
- Identify and report deviations, non-compliance and quality incidents according to local policy and trial protocols
- Where relevant, contribute to study analysis including drafting of interim study safety reports, final clinical study reports and publications.
Out of Hours Commitment
- Participate in a rotational 24-hour on-call advice service for study participants
- Provide evening and weekend clinical cover as part of the rota
- Attend site when required to assess participants out of hours
General Responsibilities
- Deals with enquiries from participants and their families with professionalism and confidentiality, reporting any concerns appropriately
- Provide professional research advice to other members of the team and external study sites
- Provide training to junior members of staff as required
- Support monitoring visits where required
- Contribute to continuous process improvement
- Have a commitment to delivering quality research at all levels
- Contribution to and approval of standard operating procedures relating to clinical activity
- Foster good communication with the trial Investigator, sites and all HCF teams and staff, as well as within the wider LSTM environment
- Act in a manner that safeguards children and at-risk adults, including LSTM staff and students, in accordance with safeguarding policies. Assess and mitigate safeguarding risks and report/refer safeguarding concerns in relation to research participants, community members, beneficiaries, staff and students.
- Maintain mandatory L3 safeguarding training in accordance with NHS requirements.
- Promote equality of opportunity and inclusive practice in all aspects of work undertaken
- Any other duties commensurate with the grade or role
Qualifications & Experience
- Full registration with the General Medical Council and current licence to practise in the UK
- Completion of Foundation Year 2 training (or equivalent)
- Previous experience in clinical research and/or audit
- Excellent communication and interpersonal skills
- Ability to work safely within research governance and ICH-GCP standards
- Willingness to participate in out-of-hours, weekend and on-call work
(For a full list of essential and desirable criteria please refer to the job description and person specification)
Enhanced with barred checks DBS and mandated DBS Update Service registration is required.
Additional benefits of joining LSTM:
- Generous occupational pension schemes
- Government backed “cycle to work” scheme.
- Affiliated, discounted staff membership to the University of Liverpool Sports Centre
- A range of additional family friendly policies
Inclusion is central to our values at LSTM.
We seek to attract and recruit people who reflect the diversity across our communities, regardless of sexual orientation, gender identity, ethnicity, nationality, faith or belief, social background, age and disability. LSTM selects candidates based on skills, qualifications, and experience.
We welcome conversations about flexible working; and applications from those returning to employment after a break from their careers.
LSTM actively promotes Equal Opportunities and Safeguarding Policies.
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Location: Liverpool
Salary: £52,656 – £65,048
Contract: Fixed term until 19/08/27
Flexible working arrangements between 0.4 and 1.0 FTE available
Role includes evening, weekend, and on-call commitments with additional payments in line with rota requirements.
Overview
Liverpool School of Tropical Medicine (LSTM) is a globally recognised centre of excellence for teaching and research in tropical diseases. Recently ranked in the top 5.3% of universities in the world, we are proud of the work we do and the impact this has on the people who need our help most.
We are seeking a motivated and proactive Study Doctor to join our Human Challenge Facility within Clinical Sciences. This is an exciting opportunity to contribute to innovative experimental medicine and controlled human infection studies that aim to accelerate the development of vaccines, diagnostics and therapeutics for populations most affected by infectious diseases globally.
Working within a multidisciplinary clinical research environment, you will provide high-quality medical oversight for research participants while ensuring studies are delivered safely, ethically and in compliance with Good Clinical Practice (GCP) and regulatory requirements.
This role is suitable for doctors with an interest in infectious diseases, immunology, acute medicine, public health, clinical pharmacology or clinical research.
Key Responsibilities
Clinical Duties
- Support human challenge and clinical trial portfolio, putting the health, safety and well-being of participants at the forefront of all activities
- Provide medical oversight of trial participants
- Maintain an excellent standard of participant care in accordance with ICH GCP, UK Policy Framework for Health and Social Care Research, LSTM Standard Operating Procedures and General Medical Council (GMC) requirements.
- Screening participants for eligibility to enter clinical studies, including providing information to participants about the study and taking informed consent
- Physical health checks including physical examination
- Interpreting ECGs, venepuncture, reviewing laboratory results for clinical significance
- Clinical review of participants before trial procedures to ensure it is safe to proceed
- Collecting information from participants relating to adverse events, reporting and assessing these events according to relevant protocols and regulations
- Provide management of medical emergencies
- Escalating clinical issues to the appropriate Investigator
- Ensure safe prescription of trial medications as per protocol and relevant regulations
- Maintain clinical skills in line with local and NHS policy
Research Responsibilities
- Work to Good Clinical Practice standards at all times
- Data collection and entry into eCRFs, respond to data management queries in a timely fashion
- Complete all relevant study training including HCF SOPs within the mandated timelines
- Contribute to study design through protocol reviews and drafting, contribute to participant facing documents
- Support study set up activities including reviewing and advising on regulatory applications (HRA, REC, MHRA) as required
- Identify and report deviations, non-compliance and quality incidents according to local policy and trial protocols
- Where relevant, contribute to study analysis including drafting of interim study safety reports, final clinical study reports and publications.
Out of Hours Commitment
- Participate in a rotational 24-hour on-call advice service for study participants
- Provide evening and weekend clinical cover as part of the rota
- Attend site when required to assess participants out of hours
General Responsibilities
- Deals with enquiries from participants and their families with professionalism and confidentiality, reporting any concerns appropriately
- Provide professional research advice to other members of the team and external study sites
- Provide training to junior members of staff as required
- Support monitoring visits where required
- Contribute to continuous process improvement
- Have a commitment to delivering quality research at all levels
- Contribution to and approval of standard operating procedures relating to clinical activity
- Foster good communication with the trial Investigator, sites and all HCF teams and staff, as well as within the wider LSTM environment
- Act in a manner that safeguards children and at-risk adults, including LSTM staff and students, in accordance with safeguarding policies. Assess and mitigate safeguarding risks and report/refer safeguarding concerns in relation to research participants, community members, beneficiaries, staff and students.
- Maintain mandatory L3 safeguarding training in accordance with NHS requirements.
- Promote equality of opportunity and inclusive practice in all aspects of work undertaken
- Any other duties commensurate with the grade or role
Qualifications & Experience
- Full registration with the General Medical Council and current licence to practise in the UK
- Completion of Foundation Year 2 training (or equivalent)
- Previous experience in clinical research and/or audit
- Excellent communication and interpersonal skills
- Ability to work safely within research governance and ICH-GCP standards
- Willingness to participate in out-of-hours, weekend and on-call work
(For a full list of essential and desirable criteria please refer to the job description and person specification)
Enhanced with barred checks DBS and mandated DBS Update Service registration is required.
Additional benefits of joining LSTM:
- Generous occupational pension schemes
- Government backed “cycle to work” scheme.
- Affiliated, discounted staff membership to the University of Liverpool Sports Centre
- A range of additional family friendly policies
Inclusion is central to our values at LSTM.
We seek to attract and recruit people who reflect the diversity across our communities, regardless of sexual orientation, gender identity, ethnicity, nationality, faith or belief, social background, age and disability. LSTM selects candidates based on skills, qualifications, and experience.
We welcome conversations about flexible working; and applications from those returning to employment after a break from their careers.
LSTM actively promotes Equal Opportunities and Safeguarding Policies.
#J-18808-Ljbffr…