Research Or Senior Scientist – Antibody Biophysics

A successful pharmaceutical company is looking for a Research Scientist or Senior Scientist with expertise in antibody/protein biophysical characterisation to join its Antibody Humanisation and Engineering team.

This is an excellent opportunity for a delivery-focused scientist who enjoys generating high-quality experimental data and wants to contribute to the future of AI/ML-driven antibody engineering and digital drug discovery.

You’ll work within a collaborative, multidisciplinary team of wet-lab and computational scientists, helping to generate critical biophysical datasets that support the development of next-generation antibody optimisation technologies.

Key responsibilities

• Generate and analyse biophysical data for antibody panels
• Assess molecule quality and purity prior to characterisation
• Evaluate properties including affinity, thermal stability, self-interaction and non-specific binding
• Collaborate closely with computational scientists to support AI/ML model development
• Present and communicate data across scientific teams
• Support development of new antibody characterisation methodologies

Ideal background

• PhD or equivalent industry experience in antibody/protein biophysical characterisation
• Hands‑on experience with techniques assessing affinity, stability and developability e.g. SPR, BLi, DSC, DSF, DLS, mass photometry, etc.
• Strong organisational and communication skills
• Ability to work effectively in cross‑functional teams
• Interest in computational antibody engineering or AI‑guided optimisation would be advantageous
• Experience with structural visualisation tools such as PyMOL would be beneficial

This role is offered on an initial 12-month contract.

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