Principal Software Engineer (Python & AI Systems) | EU

Company: C&D Talent Advisory
Apply for the Principal Software Engineer (Python & AI Systems) | EU
Location: Oxford
Job Description:

About the Hiring Process

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About the Company

Our client is an early-stage healthcare AI startup building autonomous AI clinicians capable of transforming how healthcare is delivered.

Their mission is ambitious: create AI systems that can automate clinical workflows, assist healthcare professionals, and ultimately make high-quality healthcare accessible to everyone.

Working at the intersection of AI, distributed systems, and healthcare, they’re building production-grade technology designed to solve one of humanity’s most important challenges.

  • Location: Europe (Remote)
  • Employment Type: Full-time (Permanent or B2B)
  • Level: Principal Individual Contributor
  • Work Authorization: Must be based within the European Union (hired via Deel where applicable)

About the Role

We’re looking for a Principal Software Engineer to design and build the core infrastructure powering autonomous AI clinicians.

This is a highly hands-on engineering role focused on building large-scale distributed systems, AI agents, secure healthcare infrastructure, and production-grade backend platforms. You’ll work directly with founders, hospitals, and healthcare providers to solve complex technical problems that have real-world impact.

If you’re a builder who thrives in ambiguity, enjoys solving difficult engineering challenges, and wants to shape the future of AI-powered healthcare, we’d love to hear from you.

What You’ll Do

AI Platform Engineering;

  • Architect and build AI agent systems for healthcare applications
  • Design scalable distributed backend services
  • Develop secure healthcare infrastructure handling sensitive clinical data
  • Build low-latency communication systems supporting voice and video workflows

Production Engineering;

  • Build scalable Python services powering enterprise healthcare platforms
  • Design APIs, orchestration systems, and backend infrastructure
  • Optimize system performance, scalability, and reliability
  • Improve deployment, monitoring, and operational excellence

AI Systems;

  • Build production systems around LLMs, AI agents, and reinforcement learning
  • Design agent orchestration frameworks
  • Integrate AI capabilities into real-world healthcare workflows
  • Continuously improve system accuracy and operational performance

Technical Leadership;

  • Translate ambiguous product challenges into scalable engineering solutions
  • Partner directly with founders and product teams
  • Help shape technical architecture and engineering standards
  • Mentor engineers through technical leadership and example

What We’re Looking For

Must Have;

  • 5+ years building complex production software systems
  • Strong Python engineering experience
  • Experience designing scalable distributed systems
  • Track record of building production-grade backend platforms
  • Experience turning ambiguous requirements into reliable solutions
  • Strong system design and architecture skills
  • Startup or high-growth company experience
  • High ownership and strong problem-solving mindset
  • Excellent communication skills
  • Based in Europe

Nice to Have;

  • Healthcare technology experience
  • AI, LLM, or Agentic AI experience
  • Reinforcement Learning
  • Cloud infrastructure (AWS, GCP, Azure)
  • Enterprise software experience
  • Open-source contributions
  • Background in Mathematics, Computer Science, or Physics
  • Experience building products from zero to production

What We Offer

  • €100,000–€200,000 salary
  • Meaningful equity package
  • Fully remote across Europe
  • Flexible employment (Permanent or B2B)
  • Opportunity to work directly with founders
  • High ownership from day one
  • Small, elite engineering team
  • Mission-driven work solving one of healthcare’s biggest challenges
  • Opportunity to build technology with global impact

If you’re excited about building production AI systems that could redefine the future of healthcare, we’d love to hear from you…

Posted: July 13th, 2026