Principal Scientist / Associate Scientific Director – Computational Chemistry
A leading company in the industry is seeking a Principal Scientist / Associate Scientific Director – Computational Chemistry to join their team based in the Chapel-en-le-Frith area, with a hybrid working model. Remote working from home can also be considered.
As the Principal Scientist / Associate Scientific Director, you will be instrumental in solving complex drug discovery challenges and guiding medicinal chemistry programmes.
Key Duties and Responsibilities
Your duties as the Principal Scientist / Associate Scientific Director will be varied; however, the key duties and responsibilities are as follows:
- Deliver high‑quality computational chemistry support across drug discovery programmes, from target identification through to clinical candidate nomination.
- Apply structure‑based and ligand‑based small molecule drug design methods, including docking, QSAR, pharmacophore modelling, virtual screening, MD, and QM calculations, to guide medicinal chemistry and solve complex design challenges.
- Provide expert guidance to medicinal chemists and multidisciplinary project teams, integrating computational insight with experimental data.
- Mentor and develop computational chemists, setting high standards for scientific thinking, quality, and integrity.
Role Requirements
To be successful in your application to this exciting role as the Principal Scientist / Associate Scientific Director we are looking to identify the following on your profile and past history:
- Relevant degree in computational chemistry or a closely related discipline.
- Proven industry experience in drug discovery within pharma, biotech, or CRO settings, managing client projects.
- A working knowledge and practical experience with structure‑based and ligand‑based small molecule drug design and the practical application of computational tools.
Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer.
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