Senior Manager, HR Operations

Company: OXB
Apply for the Senior Manager, HR Operations
Location: Oxford
Job Description:

Location

Oxford, GBCompany: oxfordbiom

Position

Senior Manager, HR Operations

Responsibilities

Lead, coach, and develop the HR Operations team to deliver a high-quality and scalable service.

Payroll

  • Lead and oversee payroll operations for UK and Germany, ensuring accuracy, timeliness, and compliance.
  • Manage the relationship with external payroll providers to ensure an accurate, timely payroll processing service is received.
  • In close partnership with Finance, ensure payroll operations meet compliance requirements across jurisdictions, including tax regulations, statutory reporting, and audit standards.
  • Monitor payroll inputs throughout the employee lifecycle (e.g., new hires, salary changes, variable pay, leaves of absence).
  • Lead periodic payroll reviews, reconciliations, and continuous improvement initiatives.
  • Resolve complex payroll queries and escalations in partnership with Finance and external payroll providers.

HR Systems (HRIS)

  • Oversee the optimisation, maintenance and governance of OXB’s global HR system, SuccessFactors, through collaboration with HRLT, business leaders and employees.
  • Lead HRIS projects, acting as the project manager to drive system enhancements, configurations, testing, and any data integrations.
  • Oversee system updates and ensure data accuracy, integrity and security to ensure SF remains the source of truth for all employee data.
  • Oversee the provision of reporting, dashboards and analytics to inform OXB’s leadership, to support strategic decision making.
  • Promote effective HRIS use across HR and the wider business by championing user adoption through training, documentation, and change management.

HR Delivery

  • Lead employee lifecycle process delivery – streamline workflows, ensuring efficient processes which provide employees with a best‑in‑class service.
  • Ensure consistent, compliant, and efficient execution of HR administrative processes across all regions.
  • Develop and maintain standard operating procedures (SOPs) for all HR lifecycle workflows.
  • Design and enhance HR operational processes with a strong employee‑centric mindset.
  • Partner with Talent Acquisition, HR Business Partners, Reward, Finance, IT, and other functions to ensure a seamless employee experience throughout all lifecycle touchpoints.
  • Create and monitor SLAs that drive efficiency and continuous improvement.
  • Collaborate to resolve operational issues across HR and the wider business.

HR Compliance

  • Ensure compliance with GDPR and data privacy.
  • Oversee immigration activities to ensure OXB’s compliance as a sponsor licence holder.
  • Support policy updates.

Continuous Process Improvement

  • Drive a culture of continuous improvement across HR operations to streamline processes, eliminate inefficiencies, and reduce manual work.
  • Conduct regular process reviews using Lean/Six Sigma or similar methodologies.
  • Implement automation opportunities—leveraging HRIS functionality, integrations, or digital workflow tools.
  • Ensure communications, guidance materials, and knowledge base content are clear, accessible, and user‑friendly.
  • Lead cross‑functional projects to modernize HR services and elevate the employee experience.

Qualifications

  • HR related degree or relevant progressive experience in HR operations, payroll, or HR systems.
  • Able to identify inefficiencies across payroll, HR systems, and HR delivery processes, and propose practical, scalable improvements.
  • Leads, develops, and motivates team to achieve high performance and service excellence.
  • Creates a collaborative, supportive team environment that encourages knowledge sharing and problem‑solving.
  • Communicates clearly and confidently with employees, managers, senior leaders, and external partners.
  • Able to explain complex payroll, HRIS, or process topics in simple, accessible language for non‑technical audiences.
  • Skilled at adapting communication style depending on audience, situation, and sensitivity of the topic.
  • Builds strong, trusted relationships across HR, Finance, IT, and business teams to support effective collaboration.
  • Highly organised, able to manage multiple priorities and meet deadlines in a fast‑paced environment.
  • Proactive and self‑motivated, taking ownership of issues and driving them to resolution.
  • Comfortable working both independently and collaboratively, depending on the situation.
  • A global mindset, pragmatic and flexible, able to adjust approach as business needs evolve.
  • Strong customer‑service orientation, focused on delivering a positive experience for employees and stakeholders.
  • Continuous improvement mindset, always looking for ways to enhance processes and efficiency.
  • Confident using data and insights to guide decisions and validate recommendations.
  • Demonstrates sound judgement and a balanced approach to risk, compliance, and operational needs.
  • SuccessFactors experience would be advantageous.

Benefits

  • Competitive total reward packages.
  • Wellbeing programs that support your mental and physical health.
  • Career development opportunities to help you grow and thrive.
  • Supportive, inclusive, and collaborative culture.
  • State‑of‑the‑art labs and manufacturing facilities.
  • A company that lives its values: Responsible, Responsive, Resilient, Respect.

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Posted: April 22nd, 2026